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產(chǎn)品中心抗體Polyclonal AntibodyK106714PAnti-Thioredoxin Polyclonal Antibody
產(chǎn)品型號：K106714P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：952
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產(chǎn)品分類
Anti-Thioredoxin Polyclonal Antibody
| 英文名稱 | Anti-Thioredoxin Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | TRDX;TRX;TRX1;TXN |
| 應用 | IHC |
| 稀釋比例 | IHC 1:25-100. |
| 交叉反應 | Human |
| 蛋白分子量 | 12kDa |
| Gene ID | 7295 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human Thioredoxin |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human Thioredoxin |
| Subcellular Locations | Nucleus Cytoplasm Secreted |
| Swiss Prot | P10599 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. |
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