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產(chǎn)品中心抗體Polyclonal AntibodyK106473PAnti-IL12 Polyclonal Antibody
產(chǎn)品型號：K106473P
更新時間：2022-08-15
廠商性質：生產(chǎn)廠家
訪 問 量 ：1061
010-50973130
產(chǎn)品分類
Anti-IL12 Polyclonal Antibody
| 英文名稱 | Anti-IL12 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | IL-12A;CLMF p35;IL-12 subunit p35;NKSF1;IL12A |
| 應用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應 | Human Mouse Rat |
| 蛋白分子量 | 52kDa |
| Gene ID | 3592 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human IL12 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human IL12 |
| Subcellular Locations | Cell membrane Secreted |
| Swiss Prot | P29459 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
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